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FAQs on Parasitic Marine Worm Diseases: Flukes/Digenes & (Monogene) Trematodes: Products, Manufacturer/Sources 

FAQs on: Flukes/Trematodes 1, Flukes/Trematodes 2, Flukes/Trematodes 3, Flukes/Trematodes 4,
FAQs on Flukes/Trematodes: Diagnosis/Symptomology, Etiology/Prevention, Treatments That Don't Work, Cures That Do Work, Case Histories

Related Articles: The Flatworms That Are Flukes by Bob Fenner, Marine Parasitic Disease, Parasitic Worms, Roundworms,

Related FAQs: Fish Worm Diseases 1, Marine Worm Parasites 2, Marine Worm Parasites 3, & FAQs on Marine Worm Parasites: Diagnosis/Symptomology, Etiology/Prevention, Cures That Don't Work, Cures That Do Work, Products/Manufacturers... Tapeworms/Cestodes, Leeches/Hirudineans, "Other" Worms and Worm-Like Parasites... Paravortex/Black Spot Disease, De-worming Medicines,

Fluke Tabs
PraziPro (Hikari)

API Fish Medication... Mainly Metro-, Prazi-       8/24/18
Hi Bob,
<Hey Branko>
I've been having issue obtaining Metronidazole and Praziquantel locally. I was thinking of trying out API General Cure, if manufacturer is to be trusted it contains nothing but Metro and Prazi and is very effective in treating parasitic worms on the fish.
<The Prazi/quantel is... might be cheaper if you're using very much to just buy from a pharma source. I think Hikari sells it in bulk if you have a distributor locally>
I've found a new supplier which im overall happy with except some of their fish come with some form of Monogeneans (if im not mistaken).
<VERY common>
Fresh water dip usually takes care of it, however its way too much stress for some fish and I'd like to avoid losing fish due to that stress.
After reading up on API general cure I've noticed they have wide variety of other medications in their offer, are they any good? If yes which are worth looking into?
<All their "older" offerings are efficacious. DO avoid the more modern "herbal" "fixes"... they're shams>
Other than that I've seen Everything Aquatics advertising similar medication blends, as well as 100% pure active ingredients. This is my second choice, simply because I believe it will be easier to clear API's products on customs. Please advise on what would you use if customs is not something to worry about.
<My take on all is posted on WWM. Do you have a copy of Ed Noga, Fish Disease, Diagnosis and Treatment? Either the 1st or 2d edition is highly recommended as a/the ONE source for reference>
Ps. I have discovered that Centropyge Angels can be easily kept in CU, when
introduced slowly, 0.02ppm per day, and with a chelated CU mix with 16/1 ratio of CU/citric acid (hope this helps your readers) :)
<Ah yes; I thank you>
Looking forward to your much valued advice.
Ps Happy Birthday! :)
<Ahh, again, appreciated. Bob Fenner>
Re: API Fish Medication; now Prazi avail., Centropyge dis. pic.       8/24/18

Thank you for swift reply.
Our local pharm company charges 350$ for 25 grams. While in the US 500$ 1kg. Just ridiculous.
<?! I'd contact Hikari: http://www.hikariusa.com/wp/solutions/healthaid/prazipro/
Their liquid prep. in one gallon is very useful... and already solubilized (i.e., in solution)>
Ps please refer to a pictures of Centropyge heraldi which are in attachment. What could cause that kind of damage? We did fw dip nothing fell off.
<.... can't tell much from a pic. Need sampling, microscopic examination...
Looks like a bacterially infected physically damaged area>
Fish has internal parasites it looks like it ate a whole marble
<... infection. Bob Fenner>


Gill-worm / flukes      7/20/18
Hello Bob,
<Hey Bran>
We are having an outbreak of what I believe is flukes. (transparent colorless flatworms falls of fish in FW bath). We have put fish through 10 minute fresh water dip, and many fell off however problem still occurs and we are losing fish. We have got Prazi based medicine for gill worms by Sera called Tremazol. Supposedly medicine is safe for biofilter. Manufacturer advises to do 80% water change after 6 hour treatment.
<Okay; have you used it?>
Since our system is infested and worms matured, my question is regarding parasites lifecycle and what would your suggestion be for treatment?
<Per the instructions on the packet>
How long should we keep medicine in the system in order to kill off parasite/eggs?
<Likely has to be reapplied>
I'm totally clueless about worms since we never had this issue before, FW dip usually takes care of this on the import.
<Yes... though I'd add a modicum of formalin to your pH adjusted freshwater  dips/baths. Please see WWM re: http://www.wetwebmedia.com/dips_baths.htm
We have a very strong bio filter, and system is fish only quarantine system, I assume water change is advised to remove dead worms/flukes in order to avoid having ammonia issue due to all dead worms.
<IF there is a bunch, a good deal of dead biota/mass, yes>
Which I believe wont be the case in our system due to powerful bio filter.
<Ah, good>
Kind regards,
<And you, Bob Fenner>

Re: Acclimation & Quarantine; variation of Prazi; use       10/29/15
Dear Bob,
Serbia is terrible when it comes to getting meds for our fish, so, this issue came up. I was wondering if you could shed some light on the subject :)
I managed to find a drug that containing 50mg of Prazi and 140 mg of Pyrantel Embonat (*Pyrantel pamoate)*, i failed to find any info on if it's toxic to fish. Do you have information on safety of this drug for fish?
It's used on cats, dogs, pigs, horses etc... for deworming with a mix with Prazi.

<I see this on wiki: https://en.wikipedia.org/wiki/Pyrantel_pamoate>
If it's safe to use what dosage would you recommend?
<I would NOT use this in aquariums, with fishes. As it may be toxic:
and has low solubility>
Kind regards,
<Welcome. Bob Fenner>

Re: Attn: bob-achilles tang. Prazi, Prazi-Pro... and Praziquantel, all the same      12/2/14
Hey bob,
It's been about 36 hrs since Prazi pro was assessed, and I can see the white pieces (fluke) have fallen off my my Aussie tusk and durgeon trigger. However the eye is still cloudy in achilles, I think that just may be the aftermath or scarring that just needs time to heal.
I see you have recommended praZiquantel to be added on food. Yesterday I grounded up some Nori, mixed with mysis, pe mysis and spirilla brine together, and soaked it in some Prazi pro and garlic .
I then saw on reef central not to soak Prazi pro on food. Can it be done with the Prazi pro, or does it only apply to Praziquantel?
<Yes. Nope. Read the ingredients...>
I thought getting the fish to eat it as well as swim in it could help he process.
Thanks for all you do my friend

What's in Fluke Tabs? Hi Chuck! I bought the Fluke tabs. Do you know what are the active ingredients? It's not written on the product. Thanks! Dominique <The active ingredients are Mebendazole and Trichlorfon.-Chuck>

Praziquantel Also Bob, I am wondering if you can help me. We have some incident of Trematodes in our system. These worm/fluke is in the fish and when we fresh water dip the fish, the worm came off from the fish. Some people I talk to say to treat with Praziquantel or PraziPro from Hikari. Do you have any info as far as treating the entire system with PraziPro (side effect, other problems etc). Thank you, Fred <Ah, yes. For Trematodes, treating their systems as well as fish livestock, 2 to 10 mg Praziquantel/liter (or 7.6 mg/gallon)... the lower does for Monogeneans will do it, the higher for Digenes. There are also methods (not applicable here) for injection and oral administration, baths... Cheers, Bob Fenner>

Re: Praziquantel Thanks Bob, what about PraziPro? Is it safe? <Yes... is just Praziquantel and a stabilizing agent: http://www.uskoi.com/prazipro.htm> I know it is a lot more expensive but no need to dilute. <Agreed> I heard you need to dilute Praziquantel with Vodka? <Heeee! Can use this solvent... or not> Also, how can you tell the difference between Monogeneans and Digenes. Thank you, Fred <Mmm, sorry for the added confusion. I would not worry re the digenetic Trematodes... they can/will perish along with the rest or die out quickly enough due to the lack of intermediate hosts (Di as in two... two or more other life forms to pass through before getting to their determinate host (your fishes)...), as opposed to Monogenes that have a direct life cycle. Bob Fenner>

DTHP Dear Robert, Read your web article about DTHP. Where can I get this material <Is sold as such, by itself and in concert with other materials for pet-fish use in various products... mainly labeled as Masoten, Dylox... see a LFS re if you're looking to treat small volumes. We can chat if this is for thousands, much more volume.> and have you heard of it being used against Gyrodactylus? <Yes... you can see this through a literature search... the most recent work of Ed Noga, Nelson Herwig... Bob Fenner> Steve

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